pyridine, 2,6-bis(diphenylphosphino)-

pyridine, 2,6-bis(diphenylphosphino)- - Names and Identifiers

Name	2,6-bis(diphenylphosphanyl)pyridine
Synonyms	2,6-Bis(diphenylphosphino)pyridine 2,6-bis(diphenylphosphanyl)pyridine pyridine, 2,6-bis(diphenylphosphino)- Pyridine, 2,6-bis(diphenylphosphino)- (6-diphenylphosphino-2-pyridinyl)-diphenylphosphine
CAS	64741-27-1
InChI	InChI=1/C29H23NP2/c1-5-14-24(15-6-1)31(25-16-7-2-8-17-25)28-22-13-23-29(30-28)32(26-18-9-3-10-19-26)27-20-11-4-12-21-27/h1-23H

pyridine, 2,6-bis(diphenylphosphino)- - Physico-chemical Properties

Molecular Formula	C29H23NP2
Molar Mass	447.45
Melting Point	124-125 °C
Boling Point	563.8±35.0 °C(Predicted)
Flash Point	294.8°C
Vapor Presure	3.73E-12mmHg at 25°C
pKa	-0.60±0.24(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

pyridine, 2,6-bis(diphenylphosphino)- - Introduction

2,6-bis(diphenylphosphanyl)pyridine is an organic compound with the chemical formula (C6H5)2P(C5H3N)P(C6H5)2, commonly referred to as dppp. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to light yellow crystalline solid.
-Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide and chloroform, insoluble in water.
-Melting point: about 82-85°C.

Use:
-Catalyst: 2,6-bis(diphenylphosphanyl)pyridine is an important ligand, often used in metal-catalyzed reactions. It can form complexes with metals and is used to catalyze reactions such as hydrogenation, olefin synthesis, and C- C bond formation.
-Organic synthesis: 2,6-bis(diphenylphosphanyl)pyridine can also be used as a reagent in organic synthesis. It can participate in alkylation reactions, hydrogenation reactions of olefins, reduction reactions, etc.

Preparation Method:
2,6-bis(diphenylphosphanyl)pyridine can be prepared by the following methods:
-First, pyridine is reacted with phenyl halide to generate 2-benzylpyridine.
-Then, in the reaction system of 2-benzylpyridine, diphenylphosphine is added, and a bell-closing reaction is carried out to obtain the target product.

Safety Information:
2,6-bis(diphenylphosphanyl)pyridine is generally relatively safe under normal operating conditions, but the following safety precautions still need to be followed:
-Contact: Avoid skin exposure and inhalation. In case of contact, rinse immediately with clean water.
-Storage: Should be stored in a dry, cool, well-ventilated place, away from fire and oxidizing agents.
-Waste Disposal: Correct disposal of waste in accordance with local regulations.

It should be noted that the above information is for reference only. When using chemical substances, the relevant safety procedures should be strictly observed, and the specific material safety data sheet required for the experiment should be consulted for more detailed and accurate safety information.

Last Update：2024-04-10 22:29:15